Brief Discussion on Quantitative NMR as a Quantitative Research Method for Pharmaceutical Impurity Reference Standards
Brief Discussion on Quantitative NMR as a Quantitative Research Method for Pharmaceutical Impurity Reference Standards
In impurity research, besides qualitative studies on impurities, quantitative studies are often required. This allows for a more accurate understanding of the actual impurity content and its consistency with high-performance liquid chromatography (HPLC) data, providing more reliab...
From Synthesis to Storage: A Record of Overcoming Key Impurities of Opicapone
From Synthesis to Storage: A Record of Overcoming Key Impurities of Opicapone
Opicapone is a new-generation peripheral catechol-O-methyltransferase (COMT) inhibitor. Developed by the Portuguese pharmaceutical group Bial-Portela, it was first approved by the European Union (EU) in June 2016.As an adjunctive therapy to levodopa/dopa decarboxylase inhibitors (...